Cancer-Fighting virus tested in patients with advanced tumors

NCT ID NCT05346484

Summary

This early-stage study tested the safety of an experimental treatment called VAXINIA, which is a modified virus designed to infect and kill cancer cells. It was given to 66 adults with advanced solid tumors that had spread and stopped responding to other treatments. The virus was injected directly into tumors or given through an IV, either alone or combined with an existing immunotherapy drug, to find a safe dose.

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Contacts and locations

Locations

  • Barbara Ann Karmanos Cancer Institute

    Detroit, Michigan, 48201, United States

  • City of Hope Medical Center

    Duarte, California, 91010, United States

  • Corewell Health

    Grand Rapids, Michigan, 49503, United States

  • Highlands Oncology

    Springdale, Arkansas, 72762, United States

  • Huntsman Cancer Institute

    Salt Lake City, Utah, 84112, United States

  • NEXT Oncology

    Fairfax, Virginia, 22031, United States

  • St. Vincent's Hospital

    Fitzroy, Victoria, 3065, Australia

  • Tasman Oncology Research

    Southport, Queensland, 4215, Australia

  • UC San Diego Moores Cancer Center

    La Jolla, California, 92093-0698, United States

  • University of Arizona Cancer Center

    Tucson, Arizona, 85724-5024, United States

  • University of Cincinnati

    Cincinnati, Ohio, 45219, United States

  • University of Miami

    Miami, Florida, 33136, United States

Conditions

Explore the condition pages connected to this study.