Immunotherapy's hidden danger: study probes blood vessel damage

NCT ID NCT07535944

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study will follow 200 cancer patients starting immune checkpoint inhibitors (ICIs) to see if these drugs stiffen the arteries. Researchers will measure pulse wave velocity before treatment, after 6-8 weeks, and at one year. The goal is to better understand vascular side effects like vasculitis and blood clots, which may become more common as ICI use grows.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Immune checkpoint inhibitors (ICIs) such as nivolumab, pembrolizumab, atezolizumab, ipilimumab, cemiplimab, and others

What this could lead to

If successful, this study could help doctors understand and monitor blood vessel problems caused by immunotherapy, leading to better safety guidelines.

What could go wrong

This is an early observational study with no treatment being tested. It only measures changes in artery stiffness, so it may not capture all vascular risks or lead to direct patient benefits.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

vascular disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • CHU de ROUEN

    Rouen, 76031, France

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact