Varicose vein study: is it better to treat branch veins now or later?
NCT ID NCT07445425
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looks at the best way to treat varicose veins in the legs. It compares doing everything in one procedure versus treating the main vein first and the branch veins later. About 206 people will take part, and researchers will track how many need repeat treatment, costs, and symptom relief over six months.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- radiofrequency ablation with or without foam sclerosing agent therapy
- What this could lead to
- If it works, this could show that treating branch veins later is just as effective, reducing unnecessary procedures and costs.
- What could go wrong
- This is an early-stage study with only 206 participants, so results may not apply to everyone. There is also a risk that staged treatment leads to more re-interventions.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Affiliated Hospital of Shaoxing University
Shaoxing, Zhejiang, China
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Dezhou People's Hospital
Dezhou, Shandong, China
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Guangxi Zhuang Autonomous Region People's Hospital
Nanning, Guangxi, China
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Hainan Provincial Hospital of Traditional Chinese Medicine
Haikou, Hainan, China
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Hangzhou Third People's Hospital
Hangzhou, Zhejiang, China
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Huai'an First People's Hospital
Huai'an, Jiangsu, China
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Jiangsu Province Hospital of Traditional Chinese Medicine
Nanjing, Jiangsu, China
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Peking University International Hospital
Beijing, Beijing Municipality, China
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Peking University Third Hospital
Beijing, Beijing Municipality, China
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Sir Run Run Shaw Hospital, Zhejiang University School of Medicine
Hangzhou, Zhejiang, 310000, China
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The First Affiliated Hospital of Bengbu Medical University
Bengbu, Anhui, China
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The First Affiliated Hospital of China Medical University
Shenyang, Liaoning, China
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The First Affiliated Hospital of Dalian Medical University
Dalian, Liaoning, China
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The First Affiliated Hospital of Guangxi University of Chinese Medicine
Nanning, Guangxi, China
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The First People's Hospital of Chenzhou
Chenzhou, Hunan, China
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The Second Affiliated Hospital of Nanchang University
Nanchang, Jiangxi, China
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The Second Affiliated Hospital, Zhejiang University School of Medicine
Hangzhou, Zhejiang, China
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Yantai Yuhuangding Hospital
Yantai, Shandong, China
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Zhengzhou Central Hospital
Zhengzhou, Henan, China
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Zhoukou Central Hospital
Zhoukou, Henan, China
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Zibo First Hospital
Zibo, Shandong, China
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Mapping pain during vein surgery to make it less uncomfortable
- Scientists track varicose veins from start to worse
- 10,000 people enrolled to uncover how vein disease silently progresses
- Study tests best timing for varicose vein removal
- New laser shows promise for varicose vein treatment in Head-to-Head trial
- New study pits two Vein-Closing techniques against each other