New drug cocktail shows promise in Hard-to-Treat cancers

NCT ID NCT01582191

First seen Nov 01, 2025 · Last updated May 01, 2026 · Updated 19 times

Summary

This early-stage trial tested a combination of two targeted drugs, vandetanib and everolimus, in 151 people with advanced cancers that had stopped responding to standard treatments. The main goals were to find the safest dose and see how well the drugs worked together to shrink tumors. The study focused on side effects and tumor response, offering a potential new option for patients with few alternatives.

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Contacts and locations

Locations

  • M D Anderson Cancer Center

    Houston, Texas, 77030, United States

Conditions

Explore the condition pages connected to this study.