Could a common antiviral drug help fight deadly brain cancer?

NCT ID NCT04116411

First seen Jan 05, 2026 · Last updated May 13, 2026 · Updated 21 times

Summary

This study tests whether adding the antiviral drug valganciclovir to standard treatment can help people with glioblastoma, an aggressive brain cancer. The drug targets a common virus (CMV) found in most of these tumors, which may make the cancer more aggressive. About 220 adults with newly diagnosed glioblastoma will receive either valganciclovir or a placebo alongside their usual therapy to see if it improves survival.

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Contacts and locations

Locations

  • Oslo University Hospital

    Oslo, Norway

  • SE01 Karolinska University Hospital

    Solna, Stockholm County, SE17164, Sweden

  • Stavanger University Hospital

    Stavanger, Norway

Conditions

Explore the condition pages connected to this study.