Lab-Grown vaginas: first human trial launches

NCT ID NCT05675722

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 2 times

Summary

This Phase 1 trial tests a lab-grown vaginal implant made from a patient's own cells for women with vaginal aplasia (born without a vagina). Ten participants will receive the implant to see if it is safe and can improve quality of life. The implant is designed to mimic natural vaginal tissue and avoid rejection.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

lab-grown vaginal tissue made from the patient's own cells

What this could lead to

If successful, this could offer a new treatment option for women born without a vagina, potentially avoiding the need for repeated surgeries.

What could go wrong

This is a very early Phase 1 trial with only 10 people. It is designed mainly to check safety, not effectiveness. Risks include bleeding, pain, infection, or scarring.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Mayer-Rokitansky-Kuster-Hauser syndrome mullerian aplasia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Wake Forest University Health Sciences

    RECRUITING

    Winston-Salem, North Carolina, 27157, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••