Experimental pill shows promise in shrinking esophageal tumors before surgery

NCT ID NCT06044311

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether adding a pill called vactosertib to standard chemoradiotherapy can improve outcomes for people with esophageal cancer. Participants take vactosertib for two weeks before and after standard treatment, then undergo surgery. The goal is to see if the drug helps shrink tumors and leads to better surgical results. The trial is currently on hold.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • University Hospitals Seidman Cancer Center, Case Comprehensive Cancer Center

    Cleveland, Ohio, 44106, United States

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