Experimental pill shows promise in shrinking esophageal tumors before surgery
NCT ID NCT06044311
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests whether adding a pill called vactosertib to standard chemoradiotherapy can improve outcomes for people with esophageal cancer. Participants take vactosertib for two weeks before and after standard treatment, then undergo surgery. The goal is to see if the drug helps shrink tumors and leads to better surgical results. The trial is currently on hold.
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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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University Hospitals Seidman Cancer Center, Case Comprehensive Cancer Center
Cleveland, Ohio, 44106, United States