New drug combo tested to halt uterine Pre-Cancer before it turns deadly

NCT ID NCT04576104

Summary

This study is testing if adding a common diabetes drug, metformin, to the standard hormone therapy (megestrol acetate) works better to control a uterine pre-cancer condition. It involves 51 women who are already scheduled for a hysterectomy or IUD placement. The goal is to see if the two-drug combination reduces abnormal cell growth more effectively than the standard single drug alone before their planned procedure.

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Contacts and locations

Locations

  • Cedars Sinai Medical Center

    Los Angeles, California, 90048, United States

  • Dana-Farber Cancer Institute

    Boston, Massachusetts, 02215, United States

  • Duke University Medical Center

    Durham, North Carolina, 27710, United States

  • Northwestern Medicine Central DuPage Hospital

    Winfield, Illinois, 60190, United States

  • Northwestern University

    Chicago, Illinois, 60611, United States

  • UNC Lineberger Comprehensive Cancer Center

    Chapel Hill, North Carolina, 27599, United States

  • University of Colorado

    Denver, Colorado, 80217-3364, United States

  • University of Minnesota/Masonic Cancer Center

    Minneapolis, Minnesota, 55455, United States

Conditions

Explore the condition pages connected to this study.