Surgical tool under scrutiny: could it spread cancer cells?

NCT ID NCT04586959

Recruiting now Knowledge-focused Sponsor: Anthony Costales, MD Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 2 times

Summary

This study is looking at whether using a device called a uterine manipulator during minimally invasive surgery for early stage endometrial cancer causes cancer cells to spread into the abdominal fluid. About 278 women will be randomly assigned to have surgery with or without the device. The main goal is to see if there are cancer cells in the fluid after surgery.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Uterine manipulator (a surgical device)
What this could lead to: If it works, this could show that using a uterine manipulator is safe and does not increase the risk of spreading cancer cells during surgery.
What could go wrong: This is an early-stage study looking at lab results, not long-term outcomes. It may not change current surgical practice, and the results might not apply to all patients.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

endometrial cancer endometrium neoplasm neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ENDOMETRIAL CANCER

Contacts and locations

Locations

Baylor College of Medicine
RECRUITING

Houston, Texas, 77030, United States
Baylor College of Medicine- McNair Campus
RECRUITING

Houston, Texas, 77030, United States
Ben Taub General Hospital
RECRUITING

Houston, Texas, 77030, United States
Cleveland Clinic
SUSPENDED

Cleveland, Ohio, 44195, United States
Harris Health System - Smith Clinic
RECRUITING

Houston, Texas, 77054, United States

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