Surgical tool under scrutiny: could it spread cancer cells?
NCT ID NCT04586959
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 2 times
Summary
This study is looking at whether using a device called a uterine manipulator during minimally invasive surgery for early stage endometrial cancer causes cancer cells to spread into the abdominal fluid. About 278 women will be randomly assigned to have surgery with or without the device. The main goal is to see if there are cancer cells in the fluid after surgery.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Uterine manipulator (a surgical device)
What this could lead to
If it works, this could show that using a uterine manipulator is safe and does not increase the risk of spreading cancer cells during surgery.
What could go wrong
This is an early-stage study looking at lab results, not long-term outcomes. It may not change current surgical practice, and the results might not apply to all patients.
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Baylor College of Medicine
RECRUITINGHouston, Texas, 77030, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Baylor College of Medicine- McNair Campus
RECRUITINGHouston, Texas, 77030, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Ben Taub General Hospital
RECRUITINGHouston, Texas, 77030, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Cleveland Clinic
SUSPENDEDCleveland, Ohio, 44195, United States
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Harris Health System - Smith Clinic
RECRUITINGHouston, Texas, 77054, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••