New implant aims to stop urine leakage in men

NCT ID NCT06968741

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study is testing a new device called UrOActive®, an artificial urinary sphincter, in 140 men with stress urinary incontinence (leakage when coughing, sneezing, or moving). The device is implanted to help control urine flow. The main goal is to see if it reduces leakage by at least half after 26 weeks. The trial is currently recruiting participants.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

UrOActive® artificial urinary sphincter (implantable device)

What this could lead to

If successful, this device could offer men with stress urinary incontinence a new, effective option to control leakage and improve quality of life.

What could go wrong

This is an early-stage, single-arm study with no comparison group. The device may not work for everyone, and risks include infection, device malfunction, or need for removal.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

female stress incontinence Urinary Incontinence, Stress

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Centre Hospitalier Univeritaire de Lyon - Hôpital Lyon Sud

    RECRUITING

    Pierre-Bénite, France

    Contact Email: •••••@•••••

  • Centre Hospitalier Universitaire de Lille

    RECRUITING

    Lille, France

    Contact Email: •••••@•••••

  • Centre Hospitalier Universitaire de Nantes

    RECRUITING

    Nantes, France

    Contact Email: •••••@•••••

  • Centre Hospitalier Universitaire de Rennes

    RECRUITING

    Rennes, France

    Contact Email: •••••@•••••

  • Centre Hospitalier Universitaire de Rouen

    RECRUITING

    Rouen, France

    Contact Email: •••••@•••••

  • Cleveland Clinic Foundation

    RECRUITING

    Cleveland, Ohio, 44106, United States

    Contact Email: •••••@•••••

  • Duke University

    RECRUITING

    Durham, North Carolina, 27710, United States

    Contact Email: •••••@•••••

  • Groupe Hospitalier Pitié-Salpêtrière

    RECRUITING

    Paris, France

    Contact Email: •••••@•••••

  • Hopital Foch

    RECRUITING

    Suresnes, France

    Contact Email: •••••@•••••

  • Hospitals Academics De Marseille Conception

    RECRUITING

    Marseille, France

    Contact Email: •••••@•••••

  • Mayo Clinic

    RECRUITING

    Rochester, Minnesota, 55950, United States

    Contact Email: •••••@•••••

  • Minnesota Urology

    RECRUITING

    Bloomington, Minnesota, 55420, United States

    Contact Email: •••••@•••••

  • Stanford University

    RECRUITING

    Stanford, California, 94305, United States

    Contact Email: •••••@•••••

  • University of California, Los Angeles

    RECRUITING

    Los Angeles, California, 90095, United States

    Contact Email: •••••@•••••

  • University of California, San Francisco

    RECRUITING

    San Francisco, California, 94153, United States

    Contact Email: •••••@•••••

  • University of Texas, MD Anderson

    RECRUITING

    Houston, Texas, 77030, United States

    Contact Email: •••••@•••••

  • University of Texas, Southwestern

    RECRUITING

    Dallas, Texas, 75390, United States

    Contact Email: •••••@•••••

  • Urology Clinics of North Texas

    RECRUITING

    Dallas, Texas, 75231, United States

    Contact Email: •••••@•••••

  • Urology of Virginia

    RECRUITING

    Virginia Beach, Virginia, 23462, United States

    Contact Email: •••••@•••••

  • Vanderbilt University Medical Center

    RECRUITING

    Nashville, Tennessee, 37232, United States

    Contact Email: •••••@•••••

  • Wake Forest University of Health Sciences

    RECRUITING

    Charlotte, North Carolina, 28204, United States

    Contact Email: •••••@•••••