Can light therapy boost eczema treatment? new trial tests UVB plus creams
NCT ID NCT05704205
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests whether adding narrowband UVB phototherapy (a type of light treatment) to optimized topical therapy (creams, ointments, and skin care advice) helps adults with moderate atopic eczema more than topical therapy alone. About 316 adults whose eczema is not well controlled by standard creams will be randomly assigned to receive either UVB light three times a week for 8-16 weeks plus topical care, or topical care only. The main goal is to see how many achieve a 50% reduction in eczema severity after 3 months.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Narrowband UVB phototherapy (a type of light therapy) plus optimized topical therapy (creams, ointments, and lifestyle advice)
What this could lead to
If it works, this could show that adding UVB light therapy to standard creams helps more people with eczema get clearer skin than creams alone.
What could go wrong
This is a mid-stage trial, not yet proven in large populations. UVB therapy requires frequent clinic visits and may cause skin irritation or long-term skin damage. The benefit over topical therapy alone may be small.
Disclaimer
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the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Alrijne Ziekenhuis
Leiderdorp, South Holland, Netherlands
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Amsterdam Universitair Medische Centra
Amsterdam, North Holland, 1105 AZ, Netherlands
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Bergman Clinics
Haarlem, North Holland, 2015 BJ, Netherlands
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Centrum Oosterwal
Alkmaar, North Holland, 1817 MS, Netherlands
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Dijklander Ziekenhuis
Purmerend, North Holland, 1441 RN, Netherlands
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Erasmus Medisch Centrum
Rotterdam, South Holland, 3015 GD, Netherlands
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Flevoziekenhuis
Almere Stad, Flevoland, 1315RA, Netherlands
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Huid Medisch Centrum
Amsterdam, North Holland, 1105 BJ, Netherlands
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Isala Klinieken
Zwolle, Overijssel, Netherlands
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Jeroen Bosch Ziekenhuis
's-Hertogenbosch, North Brabant, 5223 GZ, Netherlands
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Leids Universitair Medisch Centrum
Leiden, South Holland, 2333 ZA, Netherlands
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Meander Medisch Centrum
Amersfoort, Utrecht, 3813 TZ, Netherlands
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Medisch Centrum Leeuwarden
Leeuwarden, Provincie Friesland, 8934 AD, Netherlands
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OLVG
Amsterdam, North Holland, 1061 AE, Netherlands
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Reinier de Graaf Gasthuis
Delft, South Holland, 2625 AD, Netherlands
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Spaarne Gasthuis
Hoofddorp, North Holland, 2134 TM, Netherlands