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New pill could help regrow hair in severe alopecia

NCT ID NCT07023302

Ongoing Disease control Sponsor: AbbVie Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jul 31, 2026 · Updated 2 times

Summary

This study tests a daily pill called upadacitinib for people with severe alopecia areata, an immune system attack on hair follicles causing at least 25% scalp hair loss. About 123 teens and adults in Japan will take either the drug or a placebo for up to 104 weeks to see if it safely regrows hair. The goal is to reduce hair loss to 10% or less of the scalp.

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Conditions

The condition(s) this trial relates to.

alopecia areata

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ALOPECIA AREATA

Contacts and locations

Locations

  • Hamamatsu University Hospital /ID# 274639

    Hamamatsu, Shizuoka, 431-3192, Japan

  • Juntendo Tokyo Koto Geriatric Medical Center /ID# 275424

    Tokyo, 136-0075, Japan

  • Kanazawa Medical University Hospital /ID# 275521

    Kahoku-gun, Ishikawa-ken, 920-0265, Japan

  • Keio University Hospital /ID# 275640

    Shinjuku-ku, Tokyo, 160-8582, Japan

  • Kurume University Hospital /ID# 275519

    Kurume-shi, Fukuoka, 830-0011, Japan

  • Kyorin University Hospital /ID# 274882

    Mitaka-shi, Tokyo, 181-8611, Japan

  • Nagomi Dermatology Clinic /ID# 275418

    Ebina-shi, Kanagawa, 243-0432, Japan

  • Nagoya City University Hospital /ID# 275409

    Nagoya, Aichi-ken, 467-8602, Japan

  • Niigata University Medical and Dental Hospital /ID# 274775

    Niigata, Niigata, 951-8520, Japan

  • Osaka Metropolitan University Hospital /ID# 274956

    Osaka, Osaka, 545-8586, Japan

  • Rifu Dermatology Allergy Clinic /ID# 274875

    Miyagi-gun, Miyagi, 981-0112, Japan

  • Shinsaibashi Inui Dermatology Clinic. /ID# 274851

    Osaka, Osaka, 542-0081, Japan

  • Tohoku University Hospital /ID# 274931

    Sendai, Miyagi, 980-8574, Japan

  • Tokyo Medical University Hospital /ID# 274844

    Shinjuku-ku, Tokyo, 160-0023, Japan

  • Yamaguchi University Hospital /ID# 274638

    Ube, Yamaguchi, 755-8505, Japan

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