New drug may curb painful eye flares in arthritis patients

NCT ID NCT07018206

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether the drug upadacitinib can reduce how often people with axial spondyloarthritis (a type of arthritis affecting the spine) get sudden eye inflammation (acute anterior uveitis). About 200 adults who have had at least one eye flare in the past year will take the drug daily for 52 weeks. Researchers will track eye flare rates, arthritis symptoms, pain, and quality of life.

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Conditions

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As listed by the trial registrant

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Contacts and locations

Locations

  • University of Pennsylvania

    Philadelphia, Pennsylvania, 19104, United States

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