Engineered immune cells take on tough colorectal cancer

NCT ID NCT06653010

First seen Jan 25, 2026 · Last updated May 16, 2026 · Updated 11 times

Summary

This early-phase study tests a new type of universal CAR-T cell therapy (REVO-UWD-01) in 30 adults with metastatic colorectal cancer that has spread. The treatment targets a protein called GCC found on cancer cells. The main goals are to find the safest dose and check for side effects, while also seeing if tumors shrink. The study is currently suspended.

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Contacts and locations

Locations

  • First Affiliated Hospital of Xi'an Jiaotong University

    Xi'an, Shaanxi, 710061, China

  • Shenzhen Nanshan People's Hospital

    Shenzhen, Guangdong, China

Conditions

Explore the condition pages connected to this study.