Sepsis immune puzzle: scientists map cell changes to unlock hidden clues

NCT ID NCT03788772

First seen Nov 01, 2025 · Last updated Jun 11, 2026 · Updated 33 times

Summary

This study looked at how certain immune cells (antigen-presenting cells) behave in people with sepsis, a life-threatening response to infection. Researchers collected extra blood samples from 119 participants, including sepsis patients, critically ill patients without sepsis, and healthy volunteers. The goal was to understand why sepsis can weaken the immune system and lead to further infections, but no new treatment was tested.

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Contacts and locations

Locations

  • Cochin Hospital, AP-HP

    Paris, 75014, France

Conditions

Explore the condition pages connected to this study.