TB mystery: why do some patients suddenly worsen on treatment?
NCT ID NCT04052022
First seen Nov 01, 2025 · Last updated May 14, 2026 · Updated 23 times
Summary
This study looks at why some people with tuberculosis (TB) feel worse after starting treatment, even though they initially improved. Researchers will follow 140 adults on TB therapy, with or without these paradoxical reactions, using blood tests, urine samples, and PET/CT scans to track immune responses and inflammation. The goal is to better understand this puzzling reaction, not to test a new treatment.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Mexican Emerging Infectious Diseases Clinical Research Network (LaRed)
RECRUITINGAlcaldia Tlalpan, 14050, Mexico
Contact Phone: •••-•••-•••• Email: •••••@•••••
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National Institutes of Health Clinical Center
RECRUITINGBethesda, Maryland, 20892, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Conditions
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