Scientists probe GLP-1's role in Post-Bypass blood sugar woes

NCT ID NCT01803451

First seen Jun 26, 2026 ยท Last updated Jun 26, 2026

Summary

This study looks at how a hormone called GLP-1 helps control blood sugar and weight loss after gastric bypass surgery. Researchers will give a drug that blocks GLP-1 to 80 people, including those who had surgery and healthy controls, to measure its effects. The goal is to understand why some patients develop low blood sugar after surgery and how GLP-1 contributes to improved glucose metabolism.

What this could mean

Our plain-language read of the trial. This is informational only โ€” not medical advice or a prediction.

Active substance
exendin-(9-39)
What this could lead to
If successful, this could clarify why some patients develop low blood sugar after gastric bypass and point toward better management strategies.
What could go wrong
This is an early-phase, observational study with only 80 participants. It is not testing a new treatment, so direct patient benefits are uncertain.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • South Texas Veterans Health Care System

    RECRUITING

    San Antonio, Texas, 78229, United States

  • Texas Diabetes Institute - University Health System

    RECRUITING

    San Antonio, Texas, 78207, United States

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