Brain scans reveal why DBS may cause thinking problems in Parkinson's

NCT ID NCT06960096

Recruiting now Knowledge-focused Sponsor: Medical University of South Carolina Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looks at why deep brain stimulation (DBS) for Parkinson's disease can sometimes cause thinking problems. Researchers will scan the brains of 55 people with DBS implants while their device is on or off. The goal is to understand how stimulation affects brain networks, which could help doctors reduce side effects in the future.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: deep brain stimulation (DBS) combined with fMRI scanning
What this could lead to: If successful, this could help doctors choose better stimulation targets and reduce thinking problems after DBS surgery for Parkinson's.
What could go wrong: This is an early observational study with only 55 participants, so results may not apply to everyone. It is not testing a new treatment, only understanding brain changes.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Parkinson disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

DEEP BRAIN STIMULATION PARKINSON DISEASE

Contacts and locations

Locations

Medical University of South Carolina
RECRUITING

Charleston, South Carolina, 29425, United States

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