Sound waves and bubbles take on stubborn joint infections
NCT ID NCT07599865
First seen Jun 27, 2026 · Last updated Jul 31, 2026 · Updated 1 time
Summary
This study tests a new way to treat infected knee replacements. About 100 adults having surgery for an infected knee will be randomly assigned to receive either standard care or standard care plus an extra treatment. The extra treatment involves injecting antibiotics along with special microbubbles into the knee within 24 hours after surgery, then using ultrasound to activate the bubbles. The goal is to see if this approach can lower the chance of the infection coming back within two years.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Thomas Jefferson University/Rothman Institute
RECRUITINGPhiladelphia, Pennsylvania, 19107, United States
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UT Southwestern Medical Center
NOT_YET_RECRUITINGDallas, Texas, 75390, United States
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University of Pittsburgh Medical Center (UPMC)
NOT_YET_RECRUITINGPittsburgh, Pennsylvania, 15213, United States
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Other studies related to the condition(s) this trial covers.
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