New shot could fight stubborn joint infections after knee surgery

NCT ID NCT06889701

Recruiting now Disease control Sponsor: TenNor Therapeutics Inc. Source: ClinicalTrials.gov ↗

First seen Nov 01, 2025 · Last updated May 14, 2026 · Updated 27 times

Summary

This study tests a new antibiotic called TNP-2092, given as an injection into the knee joint, for people with an infection around a knee replacement. The goal is to see if it is safe and works better than standard antibiotics alone. About 33 adults with early or sudden joint infections will take part. The approach adds a local antibiotic to usual IV and oral antibiotics to try to control the infection without needing long-term suppression.

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Contacts and locations

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Study contacts

Contact

Phone: •••-•••-•••• Email: •••••@•••••
Contact

Phone: •••-•••-•••• Email: •••••@•••••

Locations

The First Affiliated Hospital of Xinjiang Medical University
RECRUITING

Ürümqi, Xinjiang, China

Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

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PERIPROSTHETIC JOINT INFECTION (PJI)