Ultrasound test may spot liver trouble early in transplant patients

NCT ID NCT03865589

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study is testing whether a special ultrasound technique, called shear wave elastography, can predict a serious liver complication called sinusoidal obstruction syndrome (SOS) in children and adults receiving bone marrow or stem cell transplants. Researchers will measure liver stiffness with ultrasound before and after transplant to see if changes can identify patients at risk. The goal is to improve early detection and help doctors tailor treatment more quickly.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Ultrasound shear wave elastography

What this could lead to

If successful, this could provide a non-invasive way to predict liver damage early after transplant, helping doctors intervene sooner.

What could go wrong

This is an observational diagnostic study, not a treatment trial. The test may not be accurate enough to change outcomes, and results may not apply to all transplant patients.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for STEM CELL TRANSPLANT COMPLICATIONS are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

disease related to hematopoietic stem cell transplant hepatic veno-occlusive disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Children's Mercy

    Kansas City, Missouri, 64108, United States

  • Dana-Farber Cancer Institute

    Boston, Massachusetts, 02215, United States

  • Duke University

    Durham, North Carolina, 27705, United States

  • Nationwide Children's Hospital

    Columbus, Ohio, 43205, United States

  • St. Jude Children's Research Hospital

    Memphis, Tennessee, 38105, United States

  • University Hospitals Cleveland Medical Center

    Cleveland, Ohio, 44106, United States

  • University of California, San Francisco

    San Francisco, California, 94143, United States