New dialysis test could prevent dangerous blood pressure drops in ICU patients

NCT ID NCT05214729

First seen Jun 24, 2026 · Last updated Jun 24, 2026

Summary

This study tested whether a fast removal of a small amount of fluid (250 ml over 15 or 30 minutes) during dialysis can predict which critically ill patients will have a drop in blood pressure. The test was done in 20 adults with acute kidney injury who were on a breathing machine and continuous dialysis. Doctors measured heart output before and after the fluid removal to see if it could identify patients whose hearts were relying on extra fluid to pump effectively.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for ACUTE KIDNEY INJURY are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Contacts and locations

Locations

  • Department of Intensive Care, Croix Rousse hospital, Hospices Civils de Lyon

    Lyon, 69004, France

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

fast ultrafiltration challenge (removal of 250 ml of fluid over 15 or 30 minutes)

What this could lead to

If this test works, it could help doctors quickly identify which patients on dialysis are at risk of low blood pressure due to low fluid volume, allowing safer fluid removal.

What could go wrong

This was a very small, early study with only 20 patients, so results may not apply to all patients. The test is also complex and requires special monitoring equipment.

Conditions

The condition(s) this trial relates to.

acute kidney injury

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.