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Chemo-Free stem cell transplant could change thalassemia treatment

NCT ID NCT06743477

Recruiting now Disease control Sponsor: Hu Peng Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 26, 2026 · Updated 1 time

Summary

This early study tests a new type of stem cell transplant called 'super transplant' for children aged 7-12 with severe thalassemia. Unlike standard transplants, this one does not require chemotherapy beforehand and aims to avoid graft-versus-host disease. Only 5 participants will be enrolled to see if donor cells can safely take hold.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Supergraft (donor stem cells given without pre-transplant chemotherapy)
What this could lead to
If it works, this could point toward a safer, simpler stem cell transplant for thalassemia patients who cannot have standard transplants.
What could go wrong
This is a very early, tiny trial (only 5 people). The approach is new and unproven in humans, so it may not work or could have unknown risks.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

beta-thalassemia major thalassemia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

STEM CELL TRANSPLANTATION

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Yunnan First People's Hospital

    RECRUITING

    Kunming, Yunnan, 650000, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

More trials for these conditions

Other studies related to the condition(s) this trial covers.