Could a simple exercise routine strengthen bones in thalassemia?
NCT ID NCT07064941
First seen Jul 22, 2026 · Last updated Jul 23, 2026 · Updated 1 time
Summary
This trial investigates whether a 12- to 36-week program of aerobic and strength exercises can improve body composition, muscle function, and bone density in adolescents and adults with thalassemia. Participants will follow a self-directed routine of 30 minutes of exercise, 5 days per week, with a choice of activities like brisk walking or strength exercises. The study compares changes during a usual-activity period to changes during the exercise period to see if weight-bearing activity can benefit bone health in this population.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- a self-directed exercise program combining aerobic and strength training
- What this could lead to
- If it works, this could point toward a simple, drug-free way to strengthen bones and muscles in people with thalassemia.
- What could go wrong
- This is a very small, early trial with only 20 participants. The exercise is self-directed, so adherence may vary, and results may not apply to everyone with thalassemia.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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UCSF Benioff Children's Hospital Oakland
Oakland, California, 94609, United States
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University of California, San Francisco
Oakland, California, 94609, United States
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