New knee implant under review: will it help patients walk without pain?

NCT ID NCT05876143

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study is following 400 people who received a U-Knee or Uni-Kroma partial knee implant to see how well it works over time. The goal is to measure how long the implant lasts and whether it improves pain and mobility. Researchers will check results at 1-2 years, 3 years, 5 years, and 10 years after surgery.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

unicondylar knee prosthesis (U-Knee / Uni-Kroma implant)

What this could lead to

If successful, this could confirm that the U-Knee/Uni-Kroma implant is a safe and effective option for people needing partial knee replacement, reducing pain and restoring mobility.

What could go wrong

This is an observational follow-up study, not a randomized trial, so results may be less definitive. Some patients may not experience improvement or could have complications like implant wear or infection.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • CHU Lyon Sud

    RECRUITING

    Pierre-Bénite, France

    Contact