Could a shot retrain the immune system to stop type 1 diabetes?

NCT ID NCT03624062

First seen Feb 15, 2026 · Last updated May 16, 2026 · Updated 11 times

Summary

This early-stage trial tested a new immunotherapy (IBC with MAS-1) in 21 adults recently diagnosed with type 1 diabetes. The goal was to see if the treatment is safe and can retrain the immune system to stop attacking the pancreas, potentially preserving the body's ability to make insulin. Participants received either the study drug or a placebo, and researchers monitored side effects and immune system changes.

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Contacts and locations

Locations

  • University of Colorado, Denver

    Aurora, Colorado, 80045, United States

Conditions

Explore the condition pages connected to this study.