New Two-Pronged attack aims to save insulin cells in kids with diabetes

NCT ID NCT05742243

Summary

This study tested whether combining two immune-modifying treatments—abatacept (a weekly injection) and nasal insulin (a spray)—could help protect the pancreas's remaining insulin-producing cells in children and young adults recently diagnosed with type 1 diabetes. The goal was to slow the disease's progression, making daily blood sugar management easier and potentially reducing the need for injected insulin. The treatment lasted 48 weeks, followed by another year of monitoring.

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Contacts and locations

Locations

  • Perth Children's Hospital

    Nedlands, Western Australia, 6009, Australia

  • Queensland Children's Hospital

    South Brisbane, Queensland, 4101, Australia

  • The Children's Hospital at Westmead

    Westmead, New South Wales, 2145, Australia

  • The Royal Children's Hospital

    Parkville, Victoria, 3052, Australia

  • The Royal Melbourne Hospital

    Parkville, Victoria, 3050, Australia

  • Women's and Children's Hospital

    North Adelaide, South Australia, 5006, Australia

Conditions

Explore the condition pages connected to this study.