Can a common bleeding drug help trauma patients on blood thinners?
NCT ID NCT07116395
First seen Jun 25, 2026 · Last updated Aug 12, 2026 · Updated 3 times
Summary
This phase 4 trial will test whether tranexamic acid (TXA), a drug that reduces bleeding, can safely lower blood loss in 200 orthopedic trauma patients who are on anticoagulants (blood thinners). Participants will have surgery for broken leg or thigh bones. The study compares those who get TXA to those who don't, looking at blood loss and hospital stay length. It aims to fill a gap in knowledge about using TXA in this higher-risk group.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- tranexamic acid (TXA)
- What this could lead to
- If it works, this could show that TXA safely reduces blood loss and transfusions in trauma patients who are on blood thinners.
- What could go wrong
- This is a single-center study with 200 patients, so results may not apply broadly. TXA could still raise clot risk in this specific group.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Community Regional Medical Center
Fresno, California, 93701, United States
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