Could a simple shot prevent brain bleeding after a fall?
NCT ID NCT04521881
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This Phase 3 trial tests whether a single injection of tranexamic acid, given within 3 hours of a mild head injury, can reduce brain bleeding, disability, and death in adults aged 50 and older. The study aims to enroll 5,000 participants and compares the drug to a placebo. If successful, it could offer an easy, low-cost way to improve outcomes after common falls.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
tranexamic acid
What this could lead to
If it works, this could provide a simple, early treatment to prevent serious complications like brain bleeding and disability after a mild head injury in older adults.
What could go wrong
This is a large trial, but the benefit may be small or not apply to everyone. Tranexamic acid can cause blood clots in some people, so risks need careful monitoring.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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St George's Hospital
RECRUITINGLondon, London, SW17 0QT, United Kingdom
Contact
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The Royal London Hospital
RECRUITINGLondon, London, E1 1FR, United Kingdom
Contact