Why one twin gets sick: NIH hunts clues in families
NCT ID NCT00055055
Summary
This study aimed to understand why some people develop autoimmune rheumatic diseases like rheumatoid arthritis or lupus while their genetically similar siblings do not. Researchers enrolled over 1,000 participants, including sibling pairs where one was affected and one was healthy, along with their parents and healthy volunteers. They compared blood tests, genetic factors, and environmental exposures over five years to identify potential causes and risk factors.
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Contacts and locations
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Locations
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NIEHS Clinical Research Unit (CRU)
Research Triangle Park, North Carolina, United States
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National Institutes of Health Clinical Center
Bethesda, Maryland, 20892, United States
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University of Wisconsin
Madison, Wisconsin, 53792, United States
Conditions
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