Could a shot every 6 months replace daily HIV prevention pills?
NCT ID NCT06513312
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests a new option for preventing HIV: a shot given under the skin every 6 months, called lenacapavir. It compares how well people stick with the shot versus taking a daily pill (Truvada). About 268 people at higher risk for HIV will take part. The goal is to see if the shot is easier to use, safe, and works as well as daily pills.
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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APHP Bichat Claude-Bernard Hospital
Paris, 75018, France
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APHP Hopital Saint-Antoine
Paris, 75012, France
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Axess Sexual Health, Liverpool University Hospitals NHS Trust
Liverpool, L7 8YE, United Kingdom
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CHU Nice Archet
Nice, 6202, France
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Caldecot Centre, Kings College Hospital, Kings College Hospital NHS Foundation Trust
London, SE5 9RS, United Kingdom
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Chelsea and Westminster Hospital NHS Foundation Trust, Clinical Research Facility, Chelsea and Westminster Hospital
London, SW10 9NH, United Kingdom
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Clinical Research Facility, University Hospitals Sussex NHS Foundation Trust
Brighton, BN2 3EW, United Kingdom
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Grahame Hayton Unit, Ambrose King Centre, Royal London Hospital, Barts Health NHS Trust
London, E11BB, United Kingdom
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Homerton Healthcare NHS Foundation Trust, Homerton University Hospital
London, E9 6SR, United Kingdom
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Hopital Avicenne
Bobigny, 93000, France
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Hopital Europeen Marseille
Marseille, 13006, France
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Hopital Saint Louis - Assistance Publique des Hopitaux de Paris
Paris, 75010, France
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Manchester University NS Foundation Trust
Manchester, M13 0FH, United Kingdom
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University Hospitals Birmingham NHS Foundation Trust, Birmingham Heartlands Hospital
Birmingham, B9 5SS, United Kingdom