Twice-Yearly shot could revolutionize HIV prevention for drug users

NCT ID NCT06101342

First seen Jun 27, 2026 · Last updated Aug 14, 2026 · Updated 2 times

Summary

This study looks at a new way to prevent HIV in people who inject drugs. It tests a shot given under the skin every 6 months (lenacapavir) and compares it to daily pills. The goal is to see how well the shot works in the body and if it is safe. About 181 people in the US are taking part.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Houston AIDS Research Team CRS

    Houston, Texas, 77030, United States

  • ICAP at Columbia University- Bronx Prevention Center

    The Bronx, New York, 10451, United States

  • Johns Hopkins Medicine Institute for Clinical and Translational Research, Clinical Research

    Baltimore, Maryland, 21287, United States

  • Rutgers New Jersey Medical School, Department of Medicine

    Newark, New Jersey, 07103, United States

  • UCLA Vine Street Clinic

    Los Angeles, California, 90038, United States

  • UCSD AntiViral Research Center (AVRC)

    San Diego, California, 92103, United States

  • University of Miami - Converge Miami Building

    Miami, Florida, 33136, United States

  • University of Pennsylvania, Division of Infectious Diseases Penn Prevention Research Unit

    Philadelphia, Pennsylvania, 19104, United States

  • West Virginia University

    Morgantown, West Virginia, 26506, United States

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