New shot aims to clear hepatitis b virus in chronic patients

NCT ID NCT07179653

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This Phase 2 trial tests an injection called TVAX-008 in 48 adults with chronic hepatitis B who have low levels of the virus. Half receive the drug, half a placebo, to see if it can clear a key virus marker (HBsAg) safely. The study is double-blind and already finished enrolling.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

TVAX-008 injection

What this could lead to

If successful, this could point toward a way to clear hepatitis B surface antigen, potentially reducing long-term liver damage and the need for ongoing medication.

What could go wrong

This is an early Phase 2 trial with only 48 participants, so results may not apply broadly. The treatment may not achieve HBsAg clearance, and side effects are still being studied.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

hepatitis B virus infection

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • NanFang Hospital

    Guangzhou, Guangdong, 20000, China