Blood test may track heart disease treatment

NCT ID NCT07196839

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study is tracking 50 adults with a heart condition called ATTR-CM to see if medications like tafamidis or acoramidis lower harmful amyloid proteins in the blood over time. Researchers will take blood samples at several visits to measure these proteins. The goal is to find out if a simple blood test can help doctors monitor how well the treatment is working.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

TTR stabilizing therapy (e.g., tafamidis or acoramidis)

What this could lead to

If successful, this could lead to a simple blood test to monitor treatment response in ATTR-CM patients.

What could go wrong

This is a small observational study (50 participants) measuring biomarkers, not clinical outcomes. It may not prove that the therapy directly improves health.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Amyloid Neuropathies, Familial amyloidosis wild type ATTR amyloidosis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • UT Southwestern Medical Center

    RECRUITING

    Dallas, Texas, 75248, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact