One-Shot knee injection tested for Year-Long arthritis relief

NCT ID NCT05079035

Summary

This study tested whether a single injection of an experimental drug called TTAX03 into the knee could provide better and longer-lasting pain relief and improved function than a simple saline injection for people with severe knee arthritis. It involved 90 adults whose pain was not helped by standard treatments like physical therapy or other injections. Researchers compared the two injections over a full year to see which one helped more people feel significantly better.

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Contacts and locations

Locations

  • Alabama Orthopaedic Center

    Birmingham, Alabama, 35243, United States

  • Gulfcoast Research Institute

    Sarasota, Florida, 34232, United States

  • Horizon Clinical Research

    La Mesa, California, 91942, United States

  • Manage Sites/The Ohio State University Wexner Medical Center, Sports Medicine The Ohio State University Wexner Medical Center, Sports Medicine

    Columbus, Ohio, 43201, United States

  • Ochsner Health Center

    Jefferson, Louisiana, 70121, United States

  • Paragon Sports Medicine

    Atlanta, Georgia, 30327, United States

  • Precision Clinical Research

    Sunrise, Florida, 33351, United States

  • Rothman Orthopaedic Institute

    Media, Pennsylvania, 19063, United States

  • Tuscon Orthopedic Institute

    Tucson, Arizona, 85712, United States

  • UAB Orthopaedic Surgery

    Birmingham, Alabama, 35205, United States

Conditions

Explore the condition pages connected to this study.