New cell therapy trial aims to slow progressive MS

NCT ID NCT07477639

Recruiting now Disease control Sponsor: Tr1X, Inc. Source: ClinicalTrials.gov ↗

First seen Mar 19, 2026 · Last updated Jun 17, 2026 · Updated 14 times

Summary

This early-stage trial tests TRX319, a cell therapy, in 39 adults with primary or secondary progressive multiple sclerosis (MS). The main goals are to check safety and find the best dose, with or without a pre-treatment called Bendamustine. Participants will receive up to three infusions over a year and undergo blood tests, MRI scans, and lumbar punctures to monitor effects.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

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Study contacts

Contact

Email: •••••@•••••
Contact

Phone: •••-•••-•••• Email: •••••@•••••

Locations

University of Kansas Medical Center
RECRUITING

Kansas City, Kansas, 66160, United States

Contact Phone: •••-•••-•••• Email: •••••@•••••
Washington University, St. Louis
RECRUITING

St Louis, Missouri, 63110, United States

Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

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MULTIPLE SCLEROSIS MULTIPLE SCLEROSIS (MS) PRIMARY PROGRESSIVE MULTIPLE SCLEROSIS (MS) SECONDARY PROGRESSIVE PRIMARY PROGRESSIVE MULTIPLE SCLEROSIS SECONDARY PROGRESSIVE MULTIPLE SCLEROSIS (SPMS) SECONDARY PROGRESSIVE MULTIPLE SCLEROSIS (SPMS)