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New study checks how well RA drug works in real life

NCT ID NCT01394276

Completed Disease control Sponsor: Hoffmann-La Roche Source: ClinicalTrials.gov ↗

First seen Jun 24, 2026 · Last updated Jun 26, 2026 · Updated 1 time

Summary

This study looked at how well the drug tocilizumab (Actemra) works for people with moderate to severe rheumatoid arthritis in everyday medical practice. Researchers followed 322 adults for 12 months after starting treatment. The main goals were to see how many patients achieved low disease activity or remission after 6 months.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
tocilizumab (RoActemra/Actemra)
What this could lead to
If successful, this study could confirm that tocilizumab works well in everyday clinical practice for controlling rheumatoid arthritis symptoms.
What could go wrong
This is an observational study, not a controlled trial, so results may be less reliable. It only follows patients for 12 months, so long-term effects are unknown.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

rheumatoid arthritis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

RHEUMATOID ARTHRITIS

Contacts and locations

Locations

  • Study site

    Coppito, Abruzzo, 67100, Italy

  • Study site

    Pescara, Abruzzo, 65100, Italy

  • Study site

    Brindisi, Apulia, 72100, Italy

  • Study site

    Casarano (LE), Apulia, 73042, Italy

  • Study site

    Foggia, Apulia, 71100, Italy

  • Study site

    Martina Franca, Apulia, 74015, Italy

  • Study site

    San Cesario di Lecce, Apulia, 73016, Italy

  • Study site

    Reggio Calabria, Calabria, 89133, Italy

  • Study site

    Avellino, Campania, 83100, Italy

  • Study site

    Gragnano, Campania, 80054, Italy

  • Study site

    Naples, Campania, 80131, Italy

  • Study site

    Naples, Campania, 80138, Italy

  • Study site

    Naples, Campania, 80144, Italy

  • Study site

    Salerno, Campania, 84131, Italy

  • Study site

    Telese Terme, Campania, 82037, Italy

  • Study site

    Bologna, Emilia-Romagna, 40138, Italy

  • Study site

    Ferrara, Emilia-Romagna, 44100, Italy

  • Study site

    Modena, Emilia-Romagna, 41100, Italy

  • Study site

    Piacenza, Emilia-Romagna, 29100, Italy

  • Study site

    Trieste, Friuli Venezia Giulia, 34142, Italy

  • Study site

    Albano Laziale, Lazio, 00041, Italy

  • Study site

    Rome, Lazio, 00128, Italy

  • Study site

    Rome, Lazio, 00145, Italy

  • Study site

    Rome, Lazio, 00152, Italy

  • Study site

    Rome, Lazio, 00168, Italy

  • Study site

    Rome, Lazio, 00189, Italy

  • Study site

    Viterbo, Lazio, 01100, Italy

  • Study site

    Arenzano, Liguria, 16011, Italy

  • Study site

    Castel Goffredo, Lombardy, 46042, Italy

  • Study site

    Gavardo, Lombardy, 25085, Italy

  • Study site

    Legnano, Lombardy, 20025, Italy

  • Study site

    Milan, Lombardy, 20157, Italy

  • Study site

    Monza, Lombardy, 20052, Italy

  • Study site

    Pavia, Lombardy, 27100, Italy

  • Study site

    Rozzano, Lombardy, 20089, Italy

  • Study site

    Saronno, Lombardy, 21047, Italy

  • Study site

    Treviglio, Lombardy, 24047, Italy

  • Study site

    Vimercate, Lombardy, 20059, Italy

  • Study site

    Agnone, Molise, 86081, Italy

  • Study site

    Cuneo, Piedmont, 12100, Italy

  • Study site

    Novara, Piedmont, 28100, Italy

  • Study site

    Turin, Piedmont, 10126, Italy

  • Study site

    Sassari, Sardinia, 07100, Italy

  • Study site

    Catania, Sicily, 95124, Italy

  • Study site

    Gazzi, Sicily, 98125, Italy

  • Study site

    Palermo, Sicily, 90127, Italy

  • Study site

    Palermo, Sicily, 90146, Italy

  • Study site

    Ancona, The Marches, 60020, Italy

  • Study site

    Iesi, The Marches, 60035, Italy

  • Study site

    Florence, Tuscany, 50139, Italy

  • Study site

    Massa, Tuscany, 54100, Italy

  • Study site

    Pisa, Tuscany, 56100, Italy

  • Study site

    Prato, Tuscany, 59100, Italy

  • Study site

    Perugia, Umbria, 06122, Italy

  • Study site

    Verona, Veneto, 37126, Italy

  • Study site

    Verona, Veneto, 37134, Italy

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