Can mint, chili, and camphor unlock the secrets of aging skin?

NCT ID NCT06444594

ENROLLING_BY_INVITATION Knowledge-focused Sponsor: Penn State University Source: ClinicalTrials.gov ↗

First seen Jul 27, 2026 · Last updated Jul 28, 2026 · Updated 1 time

Summary

This study explores how natural compounds found in mint, chili peppers, and camphor affect blood flow and sensation in the skin. Healthy adults aged 18 to 85 will have small amounts of these substances applied to their skin to measure how their nerves and blood vessels respond. The goal is to better understand how aging changes the way skin feels and reacts.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: topical gels containing menthol, capsaicin, and camphor
What this could lead to: If successful, this could help explain how aging affects skin sensation and blood flow, potentially pointing toward new ways to support skin health in older adults.
What could go wrong: This is a small early-phase study in healthy volunteers, so results may not apply to people with skin conditions or other health issues. The substances may cause skin irritation or allergic reactions.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

AGING

Contacts and locations

Locations

Noll Laboratory

University Park, Pennsylvania, 16802, United States

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