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Heart pacing experiment: three spots better than two?

NCT ID NCT02962791

Terminated Disease control Sponsor: University Hospital, Rouen Source: ClinicalTrials.gov ↗

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested whether pacing three spots in the heart instead of the usual two could improve cardiac resynchronization therapy (CRT) for people with heart failure. About 30% of patients don't respond well to standard CRT. The trial planned to enroll 36 adults with severe heart failure, but it was terminated early. Researchers measured changes in heart size and function using echocardiography.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Cardiac resynchronization therapy with stimulation of 3 ventricular sites (a device procedure)
What this could lead to
If successful, this approach could improve heart function and reduce symptoms for heart failure patients who don't respond to standard pacing.
What could go wrong
The trial was terminated early with only 36 participants, so results are limited. Triple-site pacing may not prove better than standard therapy and could carry additional risks from extra leads.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

heart failure

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CARDIAC RESYNCHRONIZATION THERAPY

Contacts and locations

Locations

  • Rouen University Hospital

    Rouen, France

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