New triple therapy aims to reverse heart damage in stiff heart condition

NCT ID NCT06655480

First seen Apr 24, 2026 · Last updated May 16, 2026 · Updated 6 times

Summary

This study tests whether a combination of three heart medications (SGLT2 inhibitor, ARNI, and MRA) can improve heart structure, function, and daily life in people with advanced heart failure with preserved ejection fraction (HFpEF). Fifty participants will receive either the triple therapy or standard care for 52 weeks. The goal is to see if the triple therapy reduces heart scarring and improves exercise ability and symptoms.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • National Medical Research Center for Cardiology, Ministry of Health of Russian Federation

    RECRUITING

    Moscow, Russia

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

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