New drug cocktail aims to shrink triple-positive breast tumors before surgery

NCT ID NCT07299890

First seen Jan 05, 2026 · Last updated May 13, 2026 · Updated 20 times

Summary

This study tests a combination of four drugs (trastuzumab, pertuzumab, palbociclib, and exemestane) given before surgery to people with early or locally advanced triple-positive breast cancer. The goal is to see if this treatment can eliminate all signs of cancer in the breast and lymph nodes at the time of surgery. About 90 participants will receive the drug combination, and researchers will monitor how well it works and what side effects occur.

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