Real-World study checks if immunotherapy works for advanced lung cancer patients

NCT ID NCT07279402

Recruiting now Disease control Sponsor: Antalya Training and Research Hospital Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 2 times

Summary

This study looks at how well the immunotherapy drug atezolizumab works as the first treatment for people with stage IV non-small cell lung cancer that has high PD-L1 levels (50% or more) and no targetable gene changes. Researchers will track 150 patients in Türkiye to see how long they live and how long the cancer stays under control during routine care. The goal is to understand if atezolizumab performs as well in everyday practice as it does in clinical trials.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: atezolizumab (an immunotherapy drug that helps the immune system fight cancer)
What this could lead to: If successful, this study could confirm that atezolizumab works well in everyday clinical practice for people with advanced lung cancer who have high PD-L1 levels.
What could go wrong: This is an observational study, not a controlled trial, so results may be less reliable. It is also limited to patients in Türkiye, which may not apply to other populations.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

non-small cell lung carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ATEZOLIZUMAB NSCLC STAGE IV PD-L1 GENE MUTATION REAL WORLD STUDY

Contacts and locations

Locations

Adana City Hospital
RECRUITING

Adana, Turkey (Türkiye)
Adnan Menderes University Faculty of Medicine Hospital
RECRUITING

Aydin, 09100, Turkey (Türkiye)
Afyonkarahisar Health Sciences University Hospital
RECRUITING

Afyonkarahisar, 03100, Turkey (Türkiye)
Ankara Atatürk Sanatoryum Training and Research Hospital
RECRUITING

Ankara, Turkey (Türkiye)
Ankara Bilkent City Hospital
NOT_YET_RECRUITING

Ankara, 06800, Turkey (Türkiye)
Ankara Oncology Training and Research Hospital
NOT_YET_RECRUITING

Ankara, 06200, Turkey (Türkiye)
Antalya City Hospital
RECRUITING

Antalya, Turkey (Türkiye)
Antalya Training and Research Hospital
RECRUITING

Antalya, 07100, Turkey (Türkiye)
Bahçelievler Memorial Hospital
NOT_YET_RECRUITING

Istanbul, 34180, Turkey (Türkiye)
Başakşehir Çam and Sakura City Hospital
RECRUITING

Istanbul, Turkey (Türkiye)
Dicle University Hospital
NOT_YET_RECRUITING

Diyarbakır, 21280, Turkey (Türkiye)
Dokuz Eylul University Faculty of Medicine Hospital
RECRUITING

Izmir, 35340, Turkey (Türkiye)
Ege University Hospital
RECRUITING

Izmir, Turkey (Türkiye)
Gaziantep City Hospital
RECRUITING

Gaziantep, Turkey (Türkiye)
Karadeniz Technical University Farabi Hospital
RECRUITING

Trabzon, 61080, Turkey (Türkiye)
Marmara Üniversitesi Pendik Eğitim ve Araştırma Hastanesi
NOT_YET_RECRUITING

Istanbul, 34899, Turkey (Türkiye)
Medical Park Samsun Hospital
NOT_YET_RECRUITING

Samsun, 55080, Turkey (Türkiye)
Memorial Ankara Hospital
NOT_YET_RECRUITING

Ankara, 06560, Turkey (Türkiye)
Mersin University Faculty of Medicine Hospital
RECRUITING

Mersin, 33110, Turkey (Türkiye)
Necmettin Erbakan University Meram Faculty of Medicine Hospital
RECRUITING

Konya, 42080, Turkey (Türkiye)
Ordu State Hospital
NOT_YET_RECRUITING

Ordu, 52200, Turkey (Türkiye)
Sakarya University Faculty of Medicine Hospital
RECRUITING

Sakarya, 54050, Turkey (Türkiye)
Trakya University Faculty of Medicine Hospital
RECRUITING

Edirne, 22030, Turkey (Türkiye)
Ümraniye Training and Research Hospital
NOT_YET_RECRUITING

Istanbul, 34766, Turkey (Türkiye)
İstanbul Medipol Mega Hospital
NOT_YET_RECRUITING

Istanbul, 34214, Turkey (Türkiye)

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