Could a Butter-Like supplement curb appetite and lower blood sugar?

NCT ID NCT07463495

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 2 times

Summary

This study is testing whether a supplement called tributyrin, which the body turns into butyrate, can help lower blood sugar and reduce appetite in people who are overweight or obese. Twelve participants will take either tributyrin or a placebo for two weeks, then switch after a break. Researchers will measure blood sugar, hunger, and calorie intake to see if the supplement has any effect.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
tributyrin (a dietary supplement that turns into butyrate in the body)
What this could lead to
If it works, this could point toward a simple supplement to help control appetite and blood sugar in people with overweight or obesity.
What could go wrong
This is a very small, early-stage trial with only 12 participants, so results may not apply widely. The supplement may have no effect or cause digestive discomfort.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • SDCA / Medical Research Laboratory

    RECRUITING

    Aarhus N, 8200, Denmark

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