Could a malaria drug help beat resistant colon cancer?

NCT ID NCT05576896

First seen Nov 01, 2025 · Last updated May 16, 2026 · Updated 26 times

Summary

This study tests whether adding hydroxychloroquine (a drug used for malaria) to standard targeted therapy can help shrink tumors in people with advanced BRAF-mutated colon cancer that has stopped responding to other treatments. About 43 adults will receive the combination to see if it improves response rates. The goal is to overcome a common resistance mechanism that limits current therapies.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for COLORECTAL CANCER are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Northwestern University

    RECRUITING

    Chicago, Illinois, 60611, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.