Spinal-fluid drug shows promise for rare breast cancer complication
NCT ID NCT01373710
First seen Nov 25, 2025 · Last updated May 24, 2026 · Updated 24 times
Summary
This study tested the drug trastuzumab, given directly into the spinal fluid, for people with HER2-positive breast cancer that spread to the lining of the brain (carcinomatous meningitis). The first part found the safest dose, and the second part checked if it could slow down nerve-related symptoms. 34 participants took part. The goal was to control the disease, not cure it, as ongoing treatment is typically needed.
Disclaimer
Read more
Show less
This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for METASTATIC BREAST CANCER are added.
By submitting, you agree to our Terms of use
Contacts and locations
Show contact details
Enter your email to view the contact information for this study.
By submitting, you agree to our Terms of use
Locations
-
CHU Grenoble
Grenoble, 38700, France
-
François Baclesse Center
Caen, Calvados, 14076, France
-
Institut Bergonié
Bordeaux, 33076, France
-
Institut Curie - Claudius Regaud Hospital
Paris, Île-de-France Region, 75248, France
-
Institut Univesitaire du Cancer de Toulouse
Toulouse, 31100, France
-
Institut du Cancer de Montpellier
Montpellier, 34298, France
-
Léon Bérard Center
Lyon, Rhone, 69373, France
-
Oscar Lambret Center
Lille, Nord, 59020, France
-
Pitie Salpetriere Hospital
Paris, Île-de-France Region, 75651, France
-
Rene Huguenin Hospital
Saint-Cloud, Haut de Seine, 92210, France
Conditions
Explore the condition pages connected to this study.