No more needles? new insulin spray could change diabetes care

NCT ID NCT05159453

Not yet recruiting Disease control Sponsor: Transdermal Delivery Solutions Corp Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests a new way to deliver insulin for type 2 diabetes: a spray applied to the skin instead of an injection. Thirty adults who already use insulin will try the spray for 21 days. Researchers will check if it keeps blood sugar in a safe range and causes less skin irritation or low blood sugar events compared to standard injected insulin.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Human insulin (same as injected insulin, but delivered through the skin via a spray)
What this could lead to: If it works, this could offer a needle-free way to deliver insulin for people with type 2 diabetes, making daily management easier and less painful.
What could go wrong: This is a small, early-stage trial with only 30 people for 21 days. The skin spray may not deliver insulin reliably or could cause skin irritation. It is not yet proven to be as effective as injections.

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Conditions

The condition(s) this trial relates to.

hyperglycemia type 2 diabetes mellitus

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

GLUCOSE, HIGH BLOOD

Contacts and locations

Locations

Langford Research Institute

Palm Beach Gardens, Florida, 33410, United States

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