Sound waves to reboot the brain after stroke?
NCT ID NCT07784751
First seen Aug 25, 2026 · Last updated Aug 26, 2026 · Updated 1 time
Summary
This early-stage trial is testing whether focused sound wave pulses applied to the head—called transcranial pulse stimulation—can help people recover from a recent ischemic stroke. The study includes adults aged 20 to 80 who had a stroke 1 to 6 months ago and still have motor or language difficulties. Participants receive six sessions over two weeks at different energy levels to find the safest dose and see if it improves movement, balance, and quality of life.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- transcranial pulse stimulation (TPS) using the NEUROLITH® system
- What this could lead to
- If it works, this could point toward a new non-invasive way to help people regain motor function and balance after a stroke.
- What could go wrong
- This is an early, small trial focused on safety and dosing, so benefits are uncertain. There are risks such as seizures, bleeding, or worsening neurological symptoms.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Phase 1/2
Runs two stages together: safety and dose first, then whether the treatment works.
- Participants
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About 9 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Aug 2026
- Expected to finish
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Aug 2027
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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Children (under 18), adults (18 to 64) and older adults (65 and over)
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
1. Age 20-80 years old. 2. Confirmed ischemic stroke verified by MRI. 3. Stroke onset between 1 month and 6 months prior to study enrollment. 4. NIHSS score of 4-25 points, with quantifiable motor or language deficits. 5. Completed acute medical care with stable vital signs.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
The full official record for this study. This one lists no contact details, but it is the first place any would appear.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Huan-Jui
Taipei, Taiwan, 24213, Taiwan
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Safety and preliminary efficacy of NXL-001 in patients with ischemic stroke
- Virtual reality rehab aims to bring stroke therapy home
- Blood clot markers may forecast stroke outcomes
- Can the brain relearn balance after a stroke? a new study tracks the process
- Could a nerve stimulator restore arm movement after stroke?
- Did pandemic waves reshape stroke treatment? a Pan-European study investigates