Promising breast cancer drug trial halted after only two patients enrolled

NCT ID NCT05744375

First seen Mar 16, 2026 · Last updated May 15, 2026 · Updated 8 times

Summary

This study tested a drug called trastuzumab deruxtecan (T-DXd) in people with advanced HER2-positive breast cancer that had stopped responding to standard therapy. The goal was to see if the drug could shrink tumors and improve quality of life. However, the trial was stopped early after only 2 out of a planned 41 participants were enrolled.

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Contacts and locations

Locations

  • Complejo Hospitalario Universitario A Coruña (CHUAC)

    A Coruña, 15006, Spain

  • Hospital Galdakao-Usansolo

    Galdakao, Vizcaya, 48960, Spain

  • Hospital General Universitario Gregorio Marañón

    Madrid, 28007, Spain

  • Hospital San Juan de Alicante

    Alicante, 03550, Spain

  • Hospital Universitario 12 de Octubre

    Madrid, 28041, Spain

  • Hospital Universitario Arnau de Vilanova de Lleida

    Lleida, 25198, Spain

  • Hospital Universitario Clínico San Cecilio

    Granada, 18016, Spain

  • Hospital Universitario La Paz

    Madrid, 28046, Spain

  • Hospital Universitario Marqués de Valdecilla

    Santander, Cantabria, 39008, Spain

  • Hospital Universitario Puerta de Hierro de Majadahonda

    Majadahonda, Madrid, 28222, Spain

  • Hospital Universitario Ramón y Cajal

    Madrid, 28034, Spain

  • Hospital Universitario San Pedro de Alcántara

    Cáceres, 10003, Spain

  • Hospital Universitario Son Espases

    Palma de Mallorca, Mallorca, 07120, Spain

  • Hospital Universitario Virgen del Rocío

    Seville, 41013, Spain

  • Hospital Universitario de Badajoz

    Badajoz, 06080, Spain

  • Hospital Universitario de Fuenlabrada

    Fuenlabrada, Madrid, 28942, Spain

  • Hospital Universitario de Jaén

    Jaén, Andalusia, 23007, Spain

  • Hospital Universitario de Jeréz De La Frontera

    Cadiz, Andalusia, 11407, Spain

  • Hospital del Mar

    Barcelona, 08003, Spain

Conditions

Explore the condition pages connected to this study.