Can a simple inhaler stop lung bleeding?
NCT ID NCT04961528
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tested whether inhaling tranexamic acid or terlipressin can quickly stop mild to severe coughing up blood (hemoptysis) without needing invasive procedures. 315 adults were randomly assigned to receive one of the two drugs or a placebo via nebulizer for 3 days. The goal was to see if these drugs could control bleeding within the first 3 days of hospitalization.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- inhaled tranexamic acid or terlipressin
- What this could lead to
- If it works, this could offer a simple, drug-based way to quickly stop coughing up blood without needing invasive procedures.
- What could go wrong
- This is a completed phase 3 trial, but results are not yet published. The drugs may not work better than placebo, and side effects are possible.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
AP-HP, Hôpital Européen Georges Pompidou
Paris, France
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