New drug duo tested in fight against recurrent childhood brain tumors
NCT ID NCT04485559
Summary
This early-stage trial is testing the safety and best doses of two oral drugs, trametinib and everolimus, given together to children and young adults whose brain tumors have come back after prior treatment. The study aims to see if blocking two different tumor growth pathways at once is more effective than either drug alone. Researchers will closely monitor side effects and how the body processes the drugs in up to 50 participants.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
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Locations
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Ann & Robert H. Lurie Children's Hospital of Chicago
RECRUITINGChicago, Illinois, 60611, United States
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Children's Hospital Los Angeles
RECRUITINGLos Angeles, California, 90027, United States
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Children's Hospital of Philadelphia
RECRUITINGPhiladelphia, Pennsylvania, 19104, United States
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Children's Minnesota
RECRUITINGMinneapolis, Minnesota, 55404, United States
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Children's National Medical Center
RECRUITINGWashington D.C., District of Columbia, 20010, United States
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Dana Farber Cancer Institute
WITHDRAWNBoston, Massachusetts, 02215, United States
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Doernbecher Children's Hospital Oregon Health & Science University
RECRUITINGPortland, Oregon, 97239, United States
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John Hopkins University
RECRUITINGBaltimore, Maryland, 21287, United States
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Joseph M. Sanzari Children's Hospital at Hackensack University Medical Center
RECRUITINGHackensack, New Jersey, 07601, United States
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New York University
RECRUITINGNew York, New York, 10016, United States
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Riley Hospital for Children
RECRUITINGIndianapolis, Indiana, 46202, United States
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University Of Texas Southwestern Medical Center
RECRUITINGDallas, Texas, 75235, United States
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University of Alabama at Birmingham, Children's of Alabama
RECRUITINGBirmingham, Alabama, 35233, United States
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University of California, San Diego Rady Children's Hospital
RECRUITINGSan Diego, California, 92123, United States
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University of California, San Francisco
RECRUITINGSan Francisco, California, 94143, United States
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University of Florida
RECRUITINGGainesville, Florida, 32610-0265, United States
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Washington University in St. Louis
RECRUITINGSt Louis, Missouri, 63110, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Conditions
Explore the condition pages connected to this study.